EGYPT
Last update	2007-02	2007-02	2010-02	2010-02
Company	Bio-Products Laboratory	Biotest Pharma GmbH	CSL-Behring	Octapharma
Name of product	Vigam	Intraglobin® F	Sandoglobulin (lyo)	Octagam 5%
Available for Hospital therapy	Yes	Yes	Registered	Yes
Available for Home therapy	-	not available for home therapy	-	Depends on legal situation,  may be used at home in general
IVIG, SCIG or IMIG	IVIG	IVIG	IVIG	IVIG
Patient´s age	Adults and pediatrics	unlimited	Adults and children	Children and adults
Présentation	Liquid	ready-to-use solution	Lyophilisat	Liquid
Concentration %	5%	5% solution	3%, 6%, 9%, 12%	5%
Content of IgG	95%	≥ 95%	≥ 96%	≥ 95%
IgG1	65	62%	60.7%	62,2% ± 2,2
IgG2	29	34%	31.9%	31,1% ± 2,3
IgG3	6	0.5%	3.8%	6,1% ± 1,6
IgG4	1	3.5%	3.6%	1,2 % ± 0,2
Content of IgA	< 0.02% w/w	≤ 2.5 mg/ml	1.2g/L (typical value)	≤ 0.2 mg/mL
Glucose, Maltose,…	Sucrose	glucose 25 mg	Sucrose	Maltose 10%
Average dosage for PID	Dependant on age and weight of patient	initial 0.4 - 0.8 g/kg, followed by 0.2 -0.8 g/kg	0.2-0.8g/kg bodyweight	0.4 g/kg b.w.
Max. Speed of infusion	3 ml/minute	2.2 mg/ml per hour	About 2.5ml/min	5 ml/kg/hour
Intervals of infusion for PID	Every 2-4 weeks to obtain IgG trough level of at least 4-6 g/L	dependent on the individual serum IgG level between 2 and 4 weeks	Usually every 2-4 weeks	every 3 to 4 weeks
Preserving	Vigam® Liquid should be stored in the dark in its carton, between 2° and 8°C.  DO NOT FREEZE.  A short period up to 3 months at 25°C is possible within the shelf-life period.	storage in refrigerator (+2 to +8 0C) - shelf-life: 2 years	3 years ≤25°C	Below 25°C
Time for reconstitution	N/A		A few minutes	none
Packaging*		containers with 20, 50, 100 or 200 ml	1g, 3g, 6g, 12g	1g, 2.5g, 5g, 10g
* May be different from country to country